Rosario A Muñoz-Clares Selected Research

Betaine-Aldehyde Dehydrogenase

1/2009	The crystal structure of a ternary complex of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa Provides new insight into the reaction mechanism and shows a novel binding mode of the 2'-phosphate of NADP+ and a novel cation binding site.
3/2006	Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.
3/2006	Betaine aldehyde dehydrogenase from Pseudomonas aeruginosa: cloning, over-expression in Escherichia coli, and regulation by choline and salt.
2/2003	Inactivation of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa and Amaranthus hypochondriacus L. leaves by disulfiram.

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Rosario A Muñoz-Clares Research Topics

Disease

6	Infections 01/2022 - 02/2003
1	Neoplasms (Cancer) 03/2009
1	Alcoholism (Alcohol Abuse) 02/2003

Drug/Important Bio-Agent (IBA)

4	Choline (Choline Chloride)IBA 11/2011 - 03/2006
4	Betaine-Aldehyde DehydrogenaseIBA 01/2009 - 02/2003
3	NitrogenIBA 01/2009 - 03/2006
3	Betaine (C.B.B.)FDA Link 01/2009 - 03/2006
3	CarbonIBA 01/2009 - 03/2006
2	Pharmaceutical PreparationsIBA 01/2022 - 03/2006
2	NAD (NADH)IBA 01/2009 - 03/2006
2	EnzymesIBA 03/2006 - 02/2003
1	AldehydesIBA 01/2022
1	PolyaminesIBA 01/2022
1	Sulfhydryl Compounds (Thiols)IBA 03/2009
1	Arsenicals (Arsenic Compounds)IBA 03/2009
1	NADP (NADPH)IBA 01/2009
1	Disulfiram (Antabuse)FDA Link 03/2006
1	betaine aldehydeIBA 03/2006
1	Glutathione (Reduced Glutathione)IBA 03/2006
1	SaltsIBA 03/2006
1	Glucose (Dextrose)FDA LinkGeneric 03/2006
1	Anti-Infective Agents (Microbicides)IBA 02/2003
1	Mitochondrial Aldehyde DehydrogenaseIBA 02/2003